Creutzfeldt-Jakob disease

noun

Creutz·​feldt-Ja·​kob disease ˈkrȯits-ˌfelt-ˈyä-(ˌ)kōb- How to pronounce Creutzfeldt-Jakob disease (audio)
variants or less commonly Creutzfeld-Jakob disease
: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

Examples of Creutzfeldt-Jakob disease in a Sentence

Recent Examples on the Web
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These include mad cow disease, which affects mostly cattle, scrapie, which affects sheep, and Creutzfeldt-Jakob disease, which kills about 350 Americans a year ‒ most within months of their first symptom. Karen Weintraub, USA TODAY, 27 June 2024 In people, the disease is fatal and called Creutzfeldt-Jakob disease. Susanne Rust, Los Angeles Times, 18 Apr. 2024 Some of the 1,848 patients who received cadaver hormone developed Creutzfeldt-Jakob disease (CJD), a rare but always fatal brain disorder caused by a type of prion known as PrP-amyloid plaques. Erin Prater, Fortune Well, 1 Feb. 2024 The treatment approach was discontinued after cases of a rare brain disorder called Creutzfeldt-Jakob disease were found to be associated with the administration of contaminated human growth hormone from cadavers. Jacqueline Howard, CNN, 29 Jan. 2024 Doctors suspected Mike could have suffered from Creutzfeldt-Jakob disease (CJD), a rare and fatal neurodegenerative disorder in which brain proteins are abnormally folded. Timothy Bella, Washington Post, 9 Nov. 2023 Odd Autopsy Three years ago, Collinge and colleagues found a disturbing collection of clumps in the brains of eight patients who had died of Creutzfeldt-Jakob disease or CJD, a fatal brain disorder. Roni Dengler, Discover Magazine, 13 Dec. 2018 Since his wife Jody died of a rare brain disease (Creutzfeldt-Jakob disease) in 2018, the coach has put even more time into his volunteer work. Ben Thomas | Bthomas@al.com, al, 7 July 2023 Other conditions linked to dementia include Huntington's disease, Parkinson's disease and Creutzfeldt-Jakob disease, which is part of a group of rare fatal brain disorders known as prion diseases. Ken Alltucker, USA TODAY, 30 May 2023

Word History

Etymology

Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of Creutzfeldt-Jakob disease was in 1963

Dictionary Entries Near Creutzfeldt-Jakob disease

creutzer

Creutzfeldt-Jakob disease

crevalle

Cite this Entry

“Creutzfeldt-Jakob disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Creutzfeldt-Jakob%20disease. Accessed 22 Nov. 2024.

Medical Definition

Creutzfeldt-Jakob disease

noun
Creutz·​feldt-Ja·​kob disease
variants also Creutzfeld-Jakob disease
: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination
abbreviation CJD

called also Jakob-Creutzfeldt disease

see variant creutzfeldt-jakob disease

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