1
: a class of immunoglobulins including antibodies that function especially in allergic reactions
2
: an antibody of the class IgE

Examples of IgE in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In an allergy, immunoglobulin E (IgE) specific to allergens (normally harmless substances that trigger an immune response in some people) may be detected in the blood. Amber J. Tresca, Verywell Health, 31 Jan. 2025 When someone with an allergy consumes these foods, their immune system produces IgE antibodies targeting the allergenic proteins. Gordon G. Chang, Newsweek, 11 Dec. 2024 But a 2023 study found that an allergic response (at least, one including the development of IgE antibodies) is probably not in play here, and psychological factors are more likely the culprit. Erica Sloan, SELF, 10 Sep. 2024 Xolair works by intercepting immune molecules called IgE, known to be a trigger in allergic reactions. Sarah Zhang, The Atlantic, 9 Sep. 2024 Xolair's dosage ranges from 75mg to 600mg every two or four weeks, with dose and frequency determined by total serum IgE level and body weight, according to Genentech. Eduardo Cuevas, USA TODAY, 17 Feb. 2024 There are also some combination at-home tests that check for both IgE and IgG antibodies. Lauren Manaker Ms, Rdn, Ld, Clec, Verywell Health, 21 Sep. 2023 Xolair is an antibody drug that acts as a sponge, binding to IgE antibodies and preventing them from latching onto these cells. Kaitlin Sullivan, NBC News, 25 Feb. 2024 Instead of producing IgE antibodies, the body may make IgG antibodies in response to certain foods. Lauren Manaker Ms, Rdn, Ld, Clec, Verywell Health, 21 Sep. 2023

Word History

First Known Use

1969, in the meaning defined at sense 1

Time Traveler
The first known use of IgE was in 1969

Dictionary Entries Near IgE

Cite this Entry

“IgE.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/IgE. Accessed 16 Feb. 2025.

Medical Definition

1
: a class of immunoglobulins including antibodies that function especially in allergic reactions
2
: an immunoglobulin of the class IgE

More from Merriam-Webster on IgE

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!