: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also lysergic acid diethylamide

Examples of LSD in a Sentence

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Yep, it’s lumped in with heavy hitters like heroin and LSD. Matt Rozo, The Mercury News, 24 Feb. 2025 According to O’Neill, Jolly West, a CIA operative and brainwashing expert, used the clinic to recruit subjects for studies on LSD in youth. Jon Blistein, Rolling Stone, 21 Feb. 2025 The lack of Blues Brothers co-creator Aykroyd meant no Jimmy Carter talking down a guy peaking on LSD. Ted Johnson, Deadline, 16 Feb. 2025 Author Tom Robbins, whose novels read like a hit of literary LSD, filled with fantastical characters, manic metaphors and counterculture whimsy, died Sunday. Reuters, NBC News, 10 Feb. 2025 See All Example Sentences for LSD

Word History

Etymology

borrowed from German, from Lysergsäure-Diäthylamid "lysergic acid diethylamide"

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of LSD was in 1950

Browse Nearby Words

Cite this Entry

“LSD.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/LSD. Accessed 3 Mar. 2025.

Kids Definition

: an illegal drug that causes abnormal sensations, extreme and changeable states of emotion, unnatural changes in the way time and space are experienced, and hallucinations and that may sometimes cause panic in response to the effects experienced

Medical Definition

: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also acid, lysergic acid diethylamide, lysergide

More from Merriam-Webster on LSD

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