: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also lysergic acid diethylamide

Examples of LSD in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Cohen teed up the confession by mentioning that Diplo, who was calling in from Los Angeles ahead of a performance at Insomniac’s Forever Midnight, previously claimed to have run the 2023 L.A. Marathon while high on LSD. Jennifer Zhan, Vulture, 1 Jan. 2025 The records also delve into the mysterious 1953 death of Frank Olson, a scientist covertly dosed with LSD who died 10 days later in a fall from a New York hotel. Andy Biggs, Newsweek, 24 Dec. 2024 Trips last a few hours, unlike the full-day trip provided by LSD. Celia Ford, Vox, 4 Nov. 2024 There, Craig and Starkey’s characters take ayahuasca and engage in a choreographed body-entwining dance that’s like ballet on LSD. Ryan Lattanzio, IndieWire, 11 Dec. 2024 See all Example Sentences for LSD 

Word History

Etymology

borrowed from German, from Lysergsäure-Diäthylamid "lysergic acid diethylamide"

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of LSD was in 1950

Dictionary Entries Near LSD

Cite this Entry

“LSD.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/LSD. Accessed 20 Jan. 2025.

Kids Definition

: an illegal drug that causes abnormal sensations, extreme and changeable states of emotion, unnatural changes in the way time and space are experienced, and hallucinations and that may sometimes cause panic in response to the effects experienced

Medical Definition

: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also acid, lysergic acid diethylamide, lysergide

More from Merriam-Webster on LSD

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!