acantholysis
noun
ac·an·thol·y·sis
ˌak-ˌan-ˈthäl-ə-səs
ˌā-ˌkan-
ˌak-ən-
plural acantholyses
-ə-ˌsēz
: loss of coherence between keratinocytes of the epidermis that is due to breakdown of desmosomal intercellular attachments and is characteristic of various conditions (as pemphigus and herpesvirus infection) marked by vesicular eruption
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Merriam-Webster unabridged
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