acetaminophen

noun

acet·​amin·​o·​phen ə-ˌsē-tə-ˈmi-nə-fən 

ˌa-sə-tə-

: a crystalline compound C₈H₉NO₂ that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine to relieve pain and fever

Examples of acetaminophen in a Sentence

Recent Examples on the Web

Over-the-Counter (OTC) Medications The American Dental Association (ADA) also recommends nonsteroidal anti-inflammatory drugs (NSAIDs) like Advil (ibuprofen) or Aleve (naproxen), along with Tylenol (acetaminophen) for acute (short-term) pain in adults and children over 12 years old. —Lindsay Curtis, Health, 25 Sep. 2024

Her autopsy found extremely high doses of diphenhydramine (the main ingredient in Benadryl) and acetaminophen (what’s found in Tylenol) in Miller’s system, along with the fentanyl. —Kavitha Surana, ProPublica, 18 Sep. 2024

Oral analgesics like Tylenol (acetaminophen) or nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aleve or Advil can provide pain relief and reduce inflammation. —Christopher Bergland, Verywell Health, 10 Sep. 2024

Someone who has a fever could take over-the-counter fever-reducers like acetaminophen or ibuprofen, for example. —Katia Hetter, CNN, 2 Aug. 2024

Word History

Etymology

acet(yl) + amino + phen(ol)

Note: Shortened from N-acetyl-p-aminophenol. Acetaminophen was introduced as a generic name roughly coincident with the introduction of the trademark preparation Tylenol, which was first marketed as "Children's Tylenol Elixir" in 1955 by McNeil Laboratories. Synthesis of the substance, as acetylamidophenol, was first reported in Berichte der Deutschen Chemischen Gesellschaft, 11. Jahrgang (Jan.-Juni, 1878), p. 232-33 (H. N. Morse, "Ueber eine neue Darstellungsmethode der Acetylamidophenole"). Its antipyretic properties were recognized by the German physician Josef von Mering in the 1893 article "Beiträge zur Kenntniss der Antipyretica" (Therapeutische Monatshefte, 7, pp. 577-87)—he also refers to it as acetylamidophenol.

First Known Use

1958, in the meaning defined above

Kids Definition

acetaminophen

noun

acet·​amin·​o·​phen ə-ˌsēt-ə-ˈmin-ə-fən 

: a crystalline compound used in medicine to relieve pain and fever

Medical Definition

acetaminophen

noun

acet·​amin·​o·​phen ə-ˌsēt-ə-ˈmin-ə-fən  ˌas-ət- 

: a crystalline compound C₈H₉NO₂ that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine instead of aspirin to relieve pain and fever

called also paracetamol

see liquiprin, panadol, tylenol