APC

1 of 2

noun

ˌā-(ˌ)pē-ˈsē 

: an armored vehicle used to transport military personnel

APC

2 of 2

abbreviation

1

activated protein C

Normally, a molecule called activated protein C, or APC, prevents clots from becoming too large by inactivating coagulation factor V.

—Jane E. Brody

2

antigen-presenting cell

In order to trigger helper T cells, exogenous protein antigens must be taken up by antigen-presenting cells (APC) and processed into peptides that bind to MHC class II molecules.

—Paola Panina-Bordignon et al.

Examples of APC in a Sentence

Recent Examples on the Web

Noun

The store is where Hunt bought his APC and Edwin jeans and a pair of 14.5 oz. —Angela Velasquez, Sourcing Journal, 5 Nov. 2024

Launched in 2023, Obituary is from APC Studios (UK) and Irish indie Magamedia for Irish pubcaster RTÉ and Hulu in the U.S. —Lynette Rice, Deadline, 17 Sep. 2024

The deal kicks off sales on the series which APC Kids is introducing to buyers this week at this Unifrance Rendez-Vous at Le Havre in Normandy, Northern France. —John Hopewell, Variety, 4 Sep. 2024

The eight soldiers were riding in an advanced Namer APC when a massive explosion killed everyone inside, the Times of Israel reported. —Brady Knox, Washington Examiner - Political News and Conservative Analysis About Congress, the President, and the Federal Government, 15 June 2024

Some gene mutations may increase the risk of NSCLC. Mutations in the following genes may increase your risk of NSCLC: CHEK2 ATM TP53 BRCA1 EGFR APC PALB2 Smoking increases the odds of a gene mutation leading to lung cancer. —Carrie Madormo, Rn, Health, 14 Aug. 2024

Holmes has been slinging her dad caps, APC jumpers, and Vibi Venezia ballet flats in her beloved butter-soft tote since 2020—the year after that traffic-stopping oatmeal cashmere moment catapulted Catherine Holstein’s brand into the big leagues. —Alice Newbold, Vogue, 12 Aug. 2024

While the outfits — from some of their favorite brands like Issey Miyake, Loewe, Comme des Garcons and APC — change from video to video, the format remains simple, featuring the couple in their California neighborhood. —Ebony-Renee Baker, refinery29.com, 7 Aug. 2024

For example, elected APC members in the House of Representatives have been pushing for the full disclosure of an audit of the Nigerian National Petroleum Corporation, the national oil company. —Matt Mossman, Foreign Affairs, 8 Mar. 2015

Word History

Etymology

Noun

armored personnel carrier

First Known Use

Noun

1952, in the meaning defined above

Medical Definition

APC

1 of 2 noun

ˌā-ˌpē-ˈsē 

: a tumor suppressor gene that in a defective form tends to be associated with a high risk of colorectal cancer

Germ-line APC mutations give rise to familial adenomatous polyposis, an inherited cancer-predisposition syndrome in which more than 100 adenomatous polyps can develop; in carriers of the mutant gene, the risk of colorectal cancer by the age of 40 years is almost 100%.

—Sanford D. Markowitz and Monica M. Bertagnolli, The New England Journal of Medicine

APC

2 of 2 abbreviation

1

activated protein C

Normally, a molecule called activated protein C, or APC, prevents clots from becoming too large by inactivating coagulation factor V.

—Jane E. Brody, The New York Times

2

antigen-presenting cell

When a T cell binds to such an APC, the T cell multiplies and launches an attack on cells that display the telltale protein-MHC complex—cells infected by a virus, foreign skin cells, or whatever.

—Sarah Richardson, Discover

3

aspirin, phenacetin, and caffeine

The now-banned ingredient phenacetin, once widely used in APC (aspirin-phenacetin-caffeine) tablets, was found to contribute heavily to kidney disease.

—Melva Weber, Vogue