apolipoprotein

noun

apo·​li·​po·​pro·​tein ˌa-pō-ˌlī-pō-ˈprō-ˌtēn 

-ˌli-,

-ˌtē-ən

: a protein that combines with a lipid to form a lipoprotein

—often used with a letter or letter and number

Examples of apolipoprotein in a Sentence

Recent Examples on the Web

Variations in certain genes, especially myosin heavy chain 9 (MYH9) and apolipoprotein L1 (APOL1), can increase the risk of kidney failure among communities of color and communities that have fewer resources. —Suchandrima Bhowmik, Health, 30 Sep. 2024

The researchers found that people on the LCHF diet had higher levels of low-density lipoprotein, also known as LDL, cholesterol and apolipoprotein B. Apolipoprotein B is a protein that coats LDL cholesterol proteins and can predict heart disease better than elevated levels of LDL cholesterol can. —Carma Hassan, CNN, 5 Mar. 2023

Heart: An apolipoprotein B (apoB) blood test, the best indicator of heart-attack risk. —Ben Court, Men's Health, 10 Mar. 2023

Mutations in the apolipoprotein E gene (APOE) are one of the strongest risk factors for late-onset Alzheimer’s. —William A. Haseltine, Forbes, 3 Oct. 2022

The bacteria-slaying, soap-like protein is an apolipoprotein called APOL3. —Shi En Kim, Smithsonian Magazine, 20 July 2021

To assess young people’s cholesterol levels, measurements were recorded periodically from 1999 to 2016 for total cholesterol, HDL, LDL, non-HDL cholesterol, triglycerides (a type of fat) and apolipoprotein B (a protein component of LDL). —Linda Searing, chicagotribune.com, 9 Oct. 2019

Schulz said those who are interested in participating first go through a genetic test done by a cheek swab to study their apolipoprotein (APOE) genes, which are found in three variants. —Tracy Maness, Houston Chronicle, 9 Apr. 2018

Instead, a blood protein known as apolipoprotein B (apoB) is a truer indicator of the threat to our arteries, the doctors say. —Roni Dengler, Science | AAAS, 8 Dec. 2017

Word History

First Known Use

1966, in the meaning defined above

Medical Definition

apolipoprotein

noun

apo·​li·​po·​pro·​tein ˌap-ə-ˌlī-pō-ˈprō-ˌtēn, -ˌlip-ō-, -ˈprōt-ē-ən 

: a protein that combines with a lipid (such as cholesterol or triglyceride) to form a lipoprotein

Note: Apolipoproteins are grouped into several classes designated by letters, such as A, B, or C, with specific class members typically identified by a number.

… some doctors are using a new cholesterol test that may better predict heart attacks, particularly among women. It looks at particles called apolipoprotein B (apoB), which are found in LDL cholesterol.

—Ladies' Home Journal

HDL particles contain equal parts of protein and cholesterol; the protein component consists mainly of apolipoprotein A-1 …

—C. Ezzell, Science News

called also apo