autoimmune

adjective

au·​to·​im·​mune ˌȯ-tō-im-ˈyün 

: of, relating to, or caused by autoantibodies or T cells that attack molecules, cells, or tissues of the organism producing them

autoimmune diseases

autoimmunity

ˌȯ-tō-im-ˈyü-nə-tē 

noun

autoimmunization

ˌȯ-tō-ˌim-yə-nə-ˈzā-shən 

 also  -im-ˌyü-

noun

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Any healthy body produces a variety of antibodies, proteins in the blood whose job is to protect the body from unwanted bacteria, viruses, and cancer cells. The cells and organs that deal with such infections make up the immune system. In some people and animals, for various reasons, the antibodies become overactive and turn on the body's healthy tissues as well; the result is an autoimmune disease—an immune response directed against one's own self. More than eighty autoimmune diseases have been identified, the best-known being type 1 diabetes, multiple sclerosis, lupus, and rheumatoid arthritis.

Examples of autoimmune in a Sentence

Recent Examples on the Web

Ivermectin and hydroxychloroquine During the pandemic, fringe groups touted two antiparasitic drugs as treatments for Covid: ivermectin, typically used for worm infections, and hydroxychloroquine, a drug used to treat malaria and certain autoimmune conditions. —Aria Bendix, NBC News, 15 Nov. 2024

Gomez has also previously been open about her experience with lupus, an autoimmune disease in which the body’s immune system attacks healthy tissues and organs. —Larisha Paul, Rolling Stone, 5 Nov. 2024

Low magnesium levels can increase susceptibility to oxidative stress and inflammation, both of which can exacerbate autoimmune diseases. —Marco Rubio, Newsweek, 2 Nov. 2024

Those drugs include insulin to treat diabetes, blood thinners to prevent clots, as well as a drug to treat leukemia and lymphoma, and treatments for autoimmune arthritis, psoriasis, Crohn’s disease and ulcerative colitis. —Kristen Jordan Shamus, Detroit Free Press, 1 Nov. 2024

Word History

Etymology

auto- + immune, after autoimmunity, borrowed from French auto-immunité

First Known Use

1952, in the meaning defined above

Kids Definition

autoimmune

adjective

au·​to·​im·​mune ˌȯt-ō-im-ˈyün 

: relating to or caused by an abnormal condition in which an organism's immune system attacks and destroys parts of its own cells or tissues

multiple sclerosis is an autoimmune disease

Medical Definition

autoimmune

adjective

au·​to·​im·​mune -im-ˈyün 

: of, relating to, or caused by antibodies or T cells that attack molecules, cells, or tissues of the organism producing them

autoimmune diseases