bortezomib

noun

bor·tez·o·mib ˌbȯr-ˈte-zō-ˌmib

: an antineoplastic drug C₁₉H₂₅BN₄O₄ administered by intravenous or subcutaneous injection especially in the treatment of multiple myeloma

Note: Bortezomib inhibits the activity of proteolytic proteasomes, which results in an increased concentration of proteins in a cell. This buildup of proteins is thought to induce apoptosis in some types of cancer cells. Bortezomib is marketed under the trademark Velcade.

Bortezomib induces apoptosis in a wide variety of cancer-cell lines and other transformed cells, yet it has relatively few toxic effects on normal cells.—