: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers
often used before another noun
BRCA genes
a BRCA mutation

Examples of BRCA in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The twins urge other young women with breast cancer in their family to be tested for the BRCA genes. Wendy Grossman Kantor, People.com, 27 Dec. 2024 Scientists developed drugs called PARP inhibitors that treat cancers stemming from the BRCA gene mutations such as breast and ovarian cancer. David Oliver, USA TODAY, 18 Dec. 2024 Hamilton noted that people who don't have the BRCA gene mutations (which increase the risk of ovarian and breast cancer) should still be proactive about screening. Sarah Scott, Verywell Health, 28 Oct. 2024 Drugs have now been developed that treat cancers linked to the BRCA mutations. Marc B. Garnick, Scientific American, 16 Apr. 2024 See all Example Sentences for BRCA 

Word History

First Known Use

1992, in the meaning defined above

Time Traveler
The first known use of BRCA was in 1992

Dictionary Entries Near BRCA

Cite this Entry

“BRCA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/BRCA. Accessed 9 Jan. 2025.

Medical Definition

: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers
often used before another noun
BRCA genes
a BRCA mutation
Last Updated: - Updated example sentences
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