ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

Better yet, pair your retinol with a moisturizer that has ceramides and hyaluronic acid, like the IT Cosmetics Confidence in Your Beauty Sleep Night Cream, for an extra dose of soothing. —Sarah Han, Allure, 7 Jan. 2025

As the skin’s barrier weakens, ceramides restore hydration and elasticity, ensuring smoother, more resilient skin that is better able to defend against environmental stressors. —Eva Crouse, Flow Space, 6 Jan. 2025

Formulated with additional ingredients ranging from ceramides to caffeine, vitamin C, and hyaluronic acid, the creams below offer an eye-popping array of benefits for any skin type. —Jenny Berg, Vogue, 5 Jan. 2025

This moisturizing spray is designed to protect ceramides, leaving your friend with a hydrated glow. —Kirsten Chanel Webber, Rolling Stone, 17 Dec. 2024

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue