: any of several diseases of humans and domestic animals usually marked by severe gastrointestinal symptoms
especially
: an acute diarrheal disease caused by an enterotoxin produced by a comma-shaped gram-negative bacillus (Vibrio cholerae synonym V. comma) when it is present in large numbers in the proximal (see proximal sense 2) part of the human small intestine
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Merriam-Webster unabridged
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