clotting factor

noun

: any of several plasma components (such as fibrinogen, prothrombin, thromboplastin, and factor VIII) that are involved in the clotting of blood

called also coagulation factor

Examples of clotting factor in a Sentence

Recent Examples on the Web
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According to the Red Cross, plasma is commonly given to trauma, burn, and shock patients, as well as people with severe liver disease or multiple clotting factor deficiencies. Kelly Phillips Erb, Forbes, 7 Dec. 2024 Finally, the doctors gave her replacement clotting factor, a classic treatment for hemophilia, and the bleeding stopped. Roxanne Khamsi, The Atlantic, 20 Sep. 2024 In one study with 54 volunteers, a single infusion led to an increase in clotting factor levels, reduced the rate of annual bleeding episodes, and enabled 94 percent of patients to stop injecting clotting factor. Jonathan Saltzman, BostonGlobe.com, 29 Jan. 2023 Researchers are investigating ways to insert functioning versions of the clotting factor gene into patients’ own cells. Veronique Greenwood, Discover Magazine, 2 Sep. 2014 And its effects are gruesome: mutations in the gene for a crucial clotting factor mean that victims can rapidly bleed to death from even small cuts. Veronique Greenwood, Discover Magazine, 27 June 2011 In one study with 54 volunteers, a single infusion led to an increase in clotting factor levels, reduced the rate of annual bleeding episodes, and enabled 94 percent of patients to stop injecting clotting factor. Jonathan Saltzman, BostonGlobe.com, 29 Jan. 2023 The treated mice bled for a significantly shorter time than untreated mice and made 3-7% of the normal level of the clotting factor, a level that would result in only mild bleeding in humans. Veronique Greenwood, Discover Magazine, 27 June 2011 The virus inserted the gene into liver cells, which proceeded to manufacture the clotting factor, and the patients maintained elevated levels of it for over 6 months. Veronique Greenwood, Discover Magazine, 12 Dec. 2011

Word History

First Known Use

1916, in the meaning defined above

Time Traveler
The first known use of clotting factor was in 1916

Dictionary Entries Near clotting factor

Cite this Entry

“Clotting factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clotting%20factor. Accessed 23 Dec. 2024.

Medical Definition

clotting factor

noun
clot·​ting factor ˈklät-iŋ- How to pronounce clotting factor (audio)
: any of several plasma components (as fibrinogen, prothrombin, and thromboplastin) that are involved in the clotting of blood

called also coagulation factor

see factor viii, plasma thromboplastin antecedent, transglutaminase compare factor v, factor vii, factor ix, factor x, factor xii, factor xiii

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