genetic mutation

noun

plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.Natalie Angier

Examples of genetic mutation in a Sentence

Recent Examples on the Web The team’s results show that purging genetic mutations can be a lengthy evolutionary process. Jeanne Timmons, Ars Technica, 29 June 2024 That result was unexpected, since an earlier report indicated that the mammoth population likely built up harmful genetic mutations, according to Love Dalén, a scientist with the Centre for Palaeogenetics of Sweden, and one of the paper’s authors. Paul Smaglik, Discover Magazine, 27 June 2024 These efforts could potentially reveal whether the microbes experienced an altered rate of genetic mutations after being marooned on the Moon, which hypothetically could provide an adaptive advantage. Becky Ferreira, WIRED, 25 June 2024 The new study found that 27 relatives with just one Christchurch gene developed symptoms around age 52, roughly five years later later than other family members with the early-onset genetic mutation. Peter Weber, theweek, 20 June 2024 See all Example Sentences for genetic mutation 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'genetic mutation.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1915, in the meaning defined above

Time Traveler
The first known use of genetic mutation was in 1915

Dictionary Entries Near genetic mutation

Cite this Entry

“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 7 Jul. 2024.

Medical Definition

genetic mutation

noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.Joseph Alper
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