1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These tumors are considered grade I or II and are generally less aggressive than high-grade gliomas. David Faris, Newsweek, 27 Feb. 2025 Injury updates Frankie Montas (high-grade lat strain) is shut down for five to seven more weeks and will need at least six weeks to ramp up once cleared. Tim Britton, The Athletic, 24 Feb. 2025 What Are the Symptoms of Measles? Some of the early symptoms of measles resemble the flu, including a high-grade fever, dry cough, runny nose, and congestion. Claire Bugos, Verywell Health, 20 Feb. 2025 The right-hander felt something in the back of his tricep when throwing his first bullpen with the Mets last week, which turned out to be a high-grade lat strain. Abbey Mastracco, New York Daily News, 19 Feb. 2025 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 3 Mar. 2025.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
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