1
: a class of immunoglobulins including antibodies that function especially in allergic reactions
2
: an antibody of the class IgE

Examples of IgE in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In an allergy, immunoglobulin E (IgE) specific to allergens (normally harmless substances that trigger an immune response in some people) may be detected in the blood. Amber J. Tresca, Verywell Health, 31 Jan. 2025 When someone with an allergy consumes these foods, their immune system produces IgE antibodies targeting the allergenic proteins. Gordon G. Chang, Newsweek, 11 Dec. 2024

Word History

First Known Use

1969, in the meaning defined at sense 1

Time Traveler
The first known use of IgE was in 1969

Browse Nearby Words

Cite this Entry

“IgE.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/IgE. Accessed 26 Mar. 2025.

Medical Definition

1
: a class of immunoglobulins including antibodies that function especially in allergic reactions
2
: an immunoglobulin of the class IgE

More from Merriam-Webster on IgE

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!