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insulin resistance
noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes
Examples of insulin resistance in a Sentence
Recent Examples on the Web
Sugar addiction may increase the risk of weight gain, insulin resistance, type 2 diabetes, inflammation, heart disease, tooth decay, and depression.
—Jamie Johnson, Verywell Health, 21 Sep. 2024
In addition to slower metabolism and weight gain, the inflammatory response of producing cytokines can contribute to insulin resistance.
—Bryant Stamford, The Courier-Journal, 5 July 2024
Interestingly, however, both low and high levels of selenium may increase the risk of insulin resistance and type 2 diabetes.
—Elizabeth Barnes, Verywell Health, 15 Aug. 2024
Type 2 diabetes is an extreme form of insulin resistance, the result of excess body fat and inflammation.
—Bryant Stamford, The Courier-Journal, 5 July 2024
See all Example Sentences for insulin resistance
These examples are programmatically compiled from various online sources to illustrate current usage of the word 'insulin resistance.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Word History
First Known Use
1927, in the meaning defined above
Time Traveler
The first known use of insulin resistance was
in 1927
Dictionary Entries Near insulin resistance
Cite this Entry
“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 5 Oct. 2024.
Medical Definition
insulin resistance
noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
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