isoniazid

noun

iso·​ni·​a·​zid ˌī-sə-ˈnī-ə-zəd How to pronounce isoniazid (audio)
: a crystalline compound C6H7N3O used in treating tuberculosis

Examples of isoniazid in a Sentence

Recent Examples on the Web
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Two medications used to treat tuberculosis, isoniazid and pyrazinamide, are known to interfere with how your body converts some tryptophan to niacin. Brittany Lubeck, Ms, Rdn, Verywell Health, 1 Aug. 2024 Examples include digoxin, chlorpromazine, and isoniazid. Sara Hoffman, Pharmd, Verywell Health, 2 July 2024 But most importantly, when an effective treatment became available, it was disseminated worldwide, and part of that happened because isoniazid was unpatentable, so costs for producing it and treating people with it remained low. Brianne Kane, Scientific American, 17 Oct. 2023 In this fashion, certain derivatives of hydrazine were discovered to be effective against Mycobacterium tuberculosis infection in mice, including the famous drug isoniazid, which is still used to this day as part of the standard treatment regimen for the lung infection. Rebecca Kreston, Discover Magazine, 27 Jan. 2016 Note:To be specific, XDR-TB is resistant to the two first-line drugs, isoniazid and rifampin, used to treat TB initially, plus any fluoroquinolone and at least one of three injectable second-line drugs (i.e., amikacin, kanamycin, or capreomycin). Rebecca Kreston, Discover Magazine, 7 Mar. 2013 Apolisi, together with a physician colleague, ensures that children in close contact with her TB patients take the daily preventive medication isoniazid for at least six months, as recommended by the WHO. Sofia Moutinho, Scientific American, 14 May 2022 Extensively drug-resistant TB (XDR-TB) is a form of MDR-TB that is resistant to isoniazid and rifampin, in addition to fluoroquinolones and injectable second-line drugs. Cnn Editorial Research, CNN, 6 June 2021 In the past decade, scientists have come up with two shorter courses: a drug called rifampin taken every day for four months; or a combination of isoniazid and rifapentine, taken once weekly for three months. Apoorva Mandavilli, New York Times, 23 Sep. 2019

Word History

Etymology

is- + nicotinic acid + hydrazide

First Known Use

1952, in the meaning defined above

Time Traveler
The first known use of isoniazid was in 1952

Dictionary Entries Near isoniazid

Cite this Entry

“Isoniazid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isoniazid. Accessed 21 Nov. 2024.

Medical Definition

isoniazid

noun
iso·​ni·​a·​zid ˌī-sə-ˈnī-ə-zəd How to pronounce isoniazid (audio)
: a crystalline compound C6H7N3O used in treating tuberculosis

called also isonicotinic acid hydrazide

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