mannosidosis

noun

man·​nos·​i·​do·​sis mə-ˌnō-sə-ˈdō-səs 

plural mannosidoses -ˌsēz 

: a rare inherited metabolic disease characterized by deficiency of an enzyme catalyzing the metabolism of mannose with resulting accumulation of mannose in the body and marked especially by facial and skeletal deformities and by intellectual disability