methotrexate
noun
meth·o·trex·ate
ˌme-thə-ˈtrek-ˌsāt 
: a toxic folic acid analog C20H22N8O5 that is used to treat certain cancers, severe psoriasis, and rheumatoid arthritis
Examples of methotrexate in a Sentence
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Treatment Prevents Progression Traditional disease-modifying anti-rheumatic drugs (DMARDs), especially methotrexate, and biologics are considered the best options for slowing down disease progression.
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Lana Barhum, Verywell Health, 5 June 2024
In the 1950s, for instance, researchers linked a drug named methotrexate to an antibody that targets carcinoembryonic antigen, a common tumor marker, and tested whether the construct could treat advanced colorectal and ovarian cancers in people.
—Jyoti Madhusoodanan, Scientific American, 1 Mar. 2024
Traditional DMARDs are first-line options, usually methotrexate or hydroxychloroquine, depending on disease severity.
—Lana Barhum, Verywell Health, 5 June 2024
Folate supplements can interact with several medications including methotrexate, sulfasalazine, anti-seizure medications, immunosuppressants, NSAIDs, barbiturates, diuretics, and pyrimethamine (an anti-malarial drug).
—Lainey Younkin, Ms, Rd, Verywell Health, 22 Mar. 2024
See all Example Sentences for methotrexate 
Lana Barhum, Verywell Health, 5 June 2024
In the 1950s, for instance, researchers linked a drug named methotrexate to an antibody that targets carcinoembryonic antigen, a common tumor marker, and tested whether the construct could treat advanced colorectal and ovarian cancers in people.
—Jyoti Madhusoodanan, Scientific American, 1 Mar. 2024
Traditional DMARDs are first-line options, usually methotrexate or hydroxychloroquine, depending on disease severity.
—Lana Barhum, Verywell Health, 5 June 2024
Folate supplements can interact with several medications including methotrexate, sulfasalazine, anti-seizure medications, immunosuppressants, NSAIDs, barbiturates, diuretics, and pyrimethamine (an anti-malarial drug).
—Lainey Younkin, Ms, Rd, Verywell Health, 22 Mar. 2024
See all Example Sentences for methotrexate
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“Methotrexate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methotrexate. Accessed 2 Jul. 2024.
Copy CitationMedical Definition
methotrexate
noun
meth·o·trex·ate
ˌmeth-ə-ˈtrek-ˌsāt
: a toxic drug C20H22N8O5 that is an analog of folic acid and is used to treat certain cancers, severe psoriasis, and rheumatoid arthritis
called also amethopterin
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