necrosis

noun

ne·​cro·​sis nə-ˈkrō-səs 

ne-

plural necroses nə-ˈkrō-ˌsēz 

ne-

: usually localized death of living tissue

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Cells die naturally after a period of time, but may also die as a result of injuries, infections, or disease. Burns produce necrosis, and the bedsores experienced by immobile or bedridden patients are a form of necrosis. The dreaded condition known as gangrene, in which the dying tissue turns black or green, is another form. When untreated, the dying cells release substances that lead to the death of surrounding cells, so untreated necrosis can lead to death. Treatment usually requires the removal of the necrotic tissue, and in severe cases can even involve amputating a limb.

Examples of necrosis in a Sentence

Recent Examples on the Web

Keep in mind that changes in skin color are typically less pronounced in people with darker skin, so ischemia and necrosis may be harder to spot.24 Changes in temperature of fingers and toes. —Alex Yampolsky, Verywell Health, 11 July 2024

One unanswered question is whether antivenom would be just as effective at preventing necrosis if it could be administered immediately, rather than after an ambulance ride to a hospital, for instance. —Sarah Kuta, Smithsonian Magazine, 22 July 2024

It is associated with variable degrees of fibrosis and muscle necrosis (tissue death). —Heather Jones, Verywell Health, 8 Aug. 2024

Our noses are complex structures packed with blood vessels and there have been various reports of filler making its way into the blood supply, blocking it and leading to necrosis (dying skin tissue), and even blindness. —Jacqueline Kilikita, refinery29.com, 2 Aug. 2024

Word History

Etymology

Late Latin, from Greek nekrōsis, from nekroun to make dead, from nekros dead body

First Known Use

1583, in the meaning defined above

Phrases Containing necrosis

• avascular necrosis
• phloem necrosis
• tumor necrosis factor

Medical Definition

necrosis

noun

ne·​cro·​sis nə-ˈkrō-səs, ne- 

plural necroses -ˌsēz 

: death of living tissue

specifically : death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease) compare necrobiosis