sertraline

noun

ser·​tra·​line ˈsər-trə-ˌlēn How to pronounce sertraline (audio)
: an antidepressant drug C17H17NCl2 administered in the form of its hydrochloride and acting to enhance serotonin activity

Examples of sertraline in a Sentence

Recent Examples on the Web
These examples are automatically compiled from online sources to illustrate current usage. Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Participants taking sertraline, for example, saw an average weight gain of 0.5 pounds at six months, but that rose to 3.2 pounds after two years, says Petimar. Don Rauf, EverydayHealth.com, 5 July 2024 For instance, a patient might be dissuaded from taking paroxetine over sertraline due to a greater short-term risk of weight gain. Don Rauf, EverydayHealth.com, 5 July 2024 Selective serotonin reuptake inhibitors fluoxetine and sertraline had the lowest occurrence. Annalisa Merelli, STAT, 5 June 2024 For these people, antidepressants such as paroxetine, sertraline and venlafaxine are recommended as alternatives, or as an addition to psychotherapy. C. Michael White, The Conversation, 8 Nov. 2023 In an analogous human study in 2016, researchers in Brazil divided 57 adults taking the antidepressant sertraline for moderate to severe depression into two groups: one attended four sessions of aerobic activity a week for 28 days, and the other did not exercise. Ferris Jabr, Scientific American, 1 Jan. 2017 Recently, Etkin and a team of researchers developed an algorithm that used EEG data to predict how patients would respond to a common antidepressant medication called sertraline. Hannah Thomasy, Discover Magazine, 6 Dec. 2021 This is where sertraline and bepridil step in, according to Johansen and her co-authors. K. N. Smith, Discover Magazine, 3 June 2015 The sertraline was there to target the siRNA at specific cell types. Neuroskeptic, Discover Magazine, 4 Aug. 2011

Word History

Etymology

perhaps from serotonin + tetrahydro (combined with four atoms of hydrogen) + naphthalene + amine

First Known Use

1983, in the meaning defined above

Time Traveler
The first known use of sertraline was in 1983

Dictionary Entries Near sertraline

Cite this Entry

“Sertraline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sertraline. Accessed 19 Nov. 2024.

Medical Definition

sertraline

noun
ser·​tra·​line ˈsər-trə-ˌlēn How to pronounce sertraline (audio)
: a drug that functions as an SSRI and is administered orally in the form of its hydrochloride C17H17NCl2·HCl especially to treat depression, anxiety, panic disorder, and obsessive-compulsive disorder

Note: Sertraline is marketed under the trademark Zoloft.

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