supergene

noun

su·​per·​gene ˈsü-pər-ˌjēn How to pronounce supergene (audio)
: a group of linked genes acting as an allelic unit especially when due to the suppression of crossing-over

Examples of supergene in a Sentence

Recent Examples on the Web
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Our analysis of all the genes inside the supergene, spearheaded by Emory researcher Wendy M. Zinzow-Kramer, showed that ESR1 is part of a large network of genes inside the supergene that predict territorial aggression. Donna L. Maney, Scientific American, 18 Feb. 2025 Sometime in history, one of those ants had experienced a mutation that replaced the supergene on one chromosome with a copy of the supergene from the other chromosome. Viviane Callier, Quanta Magazine, 8 May 2023 Researchers still have much to learn about how that supergene controls so many features — not just color, but also wing shape, and even behaviors like flight speed. Cody Cottier, Discover Magazine, 1 Feb. 2022 If parent butterflies have differing wing patterns, offspring will display the wing pattern of the dominant supergene. Joseph Castro, Discover Magazine, 16 Aug. 2011 Keough's pop supergenes add another layer. Darren Franich, EW.com, 1 Mar. 2023 However, Trible’s team found that most of the genetic differences between the ant parasites and its host relatives are in that supergene. Byelizabeth Pennisi, science.org, 6 Mar. 2023 These physical or statistical associations of genes can form a de facto supergene through linkage, and their variants combine to form haplotypes, sequences of markers across small stretches of the genome. Razib Khan, Discover Magazine, 10 Aug. 2011 The results suggested that the mechanism behind the swallowtail’s mimicry was a supergene, which commanded a whole constellation of individual genes and was therefore capable of major changes that could be easily mistaken for macromutation. Cody Cottier, Discover Magazine, 1 Feb. 2022

Word History

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of supergene was in 1949

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Cite this Entry

“Supergene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/supergene. Accessed 3 Mar. 2025.

Medical Definition

supergene

noun
su·​per·​gene ˈsü-pər-ˌjēn How to pronounce supergene (audio)
: a group of linked genes acting as an allelic unit especially when due to the suppression of crossing-over
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