vitiate
verb
vi·ti·ate
ˈvi-shē-ˌāt
vitiated; vitiating
1
: to make faulty or defective : impair
the comic impact is vitiated by obvious haste—William Styron
2
: to debase in moral or aesthetic status
a mind vitiated by prejudice
3
: to make ineffective
fraud vitiates a contract
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Merriam-Webster unabridged
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