: any of various largely nocturnal mice (genus Peromyscus) of North and Central America typically having whitish feet and underparts
especially: a common woodland mouse (P. leucopus) of North America
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In fact, the white-footed mouse is presumably the most numerous native mammal in our state.—Evan Moore, Charlotte Observer, 20 Feb. 2025 Vandegrift has speculated that mice might act as an intermediate host, but tests his team did of white-footed mice living near a research colony of deer infected with SARS‐CoV‑2 came back negative.—Jon Cohen, science.org, 29 Apr. 2024 For example, white-footed mice, the main carriers of Lyme disease, have become one of the most dominant species in their habitat as other, rarer animals have disappeared—a change that might have played a role, among other factors, in driving rising rates of Lyme disease in the United States.—Christian Thorsberg, Smithsonian Magazine, 13 May 2024 The natural reservoir for these bacteria are small mammals like the white-footed mouse.—Joshua Rapp Learn, Discover Magazine, 6 Oct. 2023 Think owls, foxes, and coyotes, who prey on white-footed mice, a vector for lyme disease that ticks catch when feeding on the mice.—Benjamin Vogt, Better Homes & Gardens, 14 June 2023 These ticks are about the size of a poppy seed and found on small mammals like the white-footed mice living in the Northeast and upper Midwest.—Jocelyn Solis-Moreira, Popular Science, 27 Mar. 2023 Ticks the size of poppy seeds pick up the parasites that cause babesiosis by feeding on white-footed mice, according to the TickEncounter Resource Center.—Laura Crimaldi, BostonGlobe.com, 19 Mar. 2023 Those parasites are usually carried by ticks, white-footed mice, and other small mammals, according to the CDC.—Erin Prater, Fortune Well, 16 Mar. 2023
: a common woodland mouse (Peromyscus leucopus) that has whitish feet and underparts and that is a reservoir for the spirochete of the genus Borrelia (B. burgdorferi) causing Lyme disease
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