locus

noun

lo·​cus ˈlō-kəs 

plural loci ˈlō-ˌsī 

-ˌkī,

-ˌkē

1

a

: the place where something is situated or occurs : site, location

was the culture of medicine in the beginning dispersed from a single focus or did it arise in several loci?

—S. C. Harvey

b

: a center of activity, attention, or concentration

in democracy the locus of power is in the people

—H. G. Rickover

2

: the set of all points whose location is determined by stated conditions

3

: the position in a chromosome of a particular gene or allele

Synonyms

• axis
• base
• capital
• center
• central
• core
• cynosure
• epicenter
• eye
• focus
• ground zero
• heart
• hub
• mecca
• navel
• nerve center
• nexus
• nucleus
• omphalos
• seat

Examples of locus in a Sentence

The area became a locus of resistance to the government.

an area of the Southwest that has been the locus of a number of New Agey movements

Recent Examples on the Web

The locus is always the president’s unspooling brain, but the precise navigation is left to the actors. —Charles McNulty, Los Angeles Times, 21 Oct. 2024

This region, surrounded by Iran, Afghanistan, Russia, and China, must be a critical locus for American foreign policy. —Ariel Cohen, Forbes, 16 Sep. 2024

Reconstruction of the human amylase locus reveals ancient duplications seeding modern-day variation Postdoctoral Associate with the Jackson Laboratory for Genomic Medicine. —Paul Smaglik, Discover Magazine, 18 Oct. 2024

Living with her parents and three younger siblings, Ahmet, Dweezil and Diva, in a sprawling Laurel Canyon house that became a locus of work and play for three decades, Moon struggled to find her own safe harbor away from the high-intensity chaos of her domestic life. —Marc Weingarten, Los Angeles Times, 13 Aug. 2024

Word History

Etymology

Latin — more at stall

First Known Use

1648, in the meaning defined at sense 1a

Phrases Containing locus

• locus ceruleus
• locus classicus
• locus coeruleus

Kids Definition

locus

noun

lo·​cus ˈlō-kəs 

plural loci ˈlō-ˌsī 

-ˌkī,

-ˌkē

1

: place entry 1 sense 3a, locality

2

: the set of all points whose location is determined by stated conditions

3

: the position in a chromosome of a particular gene or allele

Medical Definition

locus

noun

lo·​cus ˈlō-kəs 

plural loci

ˈlō-ˌsī, -ˌkī also -ˌkē

1

: a place or site of an event, activity, or thing

the integrity of the tissues determines the extent and locus of the damage

—Sylvia E. Hines

2

: the position in a chromosome of a particular gene or allele

Legal Definition

locus

noun

lo·​cus ˈlō-kəs 

: the place connected with a particular event having legal significance