autoreactive
adjective
au·to·re·ac·tive
ˌȯt-ō-rē-ˈak-tiv
: produced by an organism and acting against its own cells or tissues
It has been presumed that autoreactive B cells, like normal B cells, accumulate in the follicles of lymphoid tissues after encountering antigen and begin to proliferate, producing high-affinity autoantibodies and forming germinal centers.—Yang-Xin Fu and Ursula Storb, Science
autoreactivity
noun
plural autoreactivities
At the same time, autoreactivity of B cells and T cells is present in all normal persons, and a complex set of regulatory mechanisms is required to prevent overt destruction of tissue through autoimmunity.
—Peter K. Gregersen, The New England Journal of Medicine
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