chronic fatigue syndrome

noun

: a disorder of unknown cause that is characterized by persistent profound fatigue usually accompanied by other symptoms (such as headache and tender lymph nodes) unrelated to any preexisting medical condition

—abbreviation CFS

Examples of chronic fatigue syndrome in a Sentence

Recent Examples on the Web

People who have had COVID-19 are more likely to develop chronic fatigue syndrome, officially known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). —Melissa Rudy, Fox News, 26 Jan. 2025

Finally, though, Dr. Shepherd received a diagnosis that not only changed his life, but also led him to help others dealing with the same issue: myalgic encephalomyelitis/chronic fatigue syndrome, better known as ME/CFS. —Katie Camero, SELF, 17 Dec. 2024

Instead, 45 mg a day might be more effective for neurological long Covid symptoms like brain fog and chronic fatigue syndrome. —Anuradha Varanasi, Forbes, 6 Nov. 2024

Around 22% of long Covid patients are unemployed and unable to work due to chronic fatigue syndrome or myalgic encephalomyelitis and brain fog. —Anuradha Varanasi, Forbes, 6 Nov. 2024

Word History

First Known Use

1947, in the meaning defined above

Medical Definition

chronic fatigue syndrome

noun

: a disorder of uncertain cause that is characterized by persistent profound fatigue usually accompanied by impairment in short-term memory or concentration, sore throat, tender lymph nodes, muscle or joint pain, and headache unrelated to any preexisting medical condition and that typically has an onset at about 30 years of age

—abbreviation CFS

called also myalgic encephalomyelitis