diltiazem

noun

dil·​ti·​a·​zem dil-ˈtī-ə-(ˌ)zem 

: a calcium channel blocker C₂₂H₂₆N₂O₄S used especially in the form of its hydrochloride as a coronary vasodilator

Examples of diltiazem in a Sentence

Recent Examples on the Web

There are other calcium blockers that might not have the same side effect, and the cardiologist might try one related to amlodipine (like nifedipine) or unrelated (like diltiazem). —Dr. Keith Roach, oregonlive, 7 Jan. 2022

The researchers were able to directly connect the opsin signaling cascade to this change in feeding behavior by introducing a blocker of opsin signaling, cis-diltiazem. —Christie Wilcox, Discover Magazine, 5 Mar. 2012

Studies in mice narrowed the search to just one candidate, the calciumchannel blocker diltiazem, which is normally used to treat hypertension. —Neil Savage, Scientific American, 18 Sep. 2019

The staff normally would have administered diltiazem, also known as Cardizem, that is used to steady an abnormal heart rate. —Katie Thomas, New York Times, 1 July 2018

But diltiazem was out of stock, and when two other drugs — adenosine and metoprolol — didn’t work, Mr. Alsina was admitted overnight. —Katie Thomas, New York Times, 1 July 2018

There isn’t any diltiazem, a one-time staple to treat rapid heart rate. —Erika Fry, Fortune, 22 May 2018

Documents in the case showed that in 1998 Ben Venue Laboratories, an Ohio company that produced the heart medication diltiazem, paid GPO fees that exceeded half its sales on the drug. —Phillip L. Zweig and, WSJ, 7 May 2018

Word History

Etymology

probably from International Scientific Vocabulary dilator + benzothiazepin, tricyclic compound structurally similar to benzodiazepine + -m (as in diazepam)

First Known Use

1975, in the meaning defined above

Medical Definition

diltiazem

noun

dil·​ti·​a·​zem dil-ˈtī-ə-(ˌ)zem 

: a calcium channel blocker used especially in the form of its hydrochloride C₂₂H₂₆N₂O₄S·HCl as a coronary vasodilator see cardizem