end-organ

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adjective

: of or relating to an organ (as the liver or kidney) that is ultimately affected by a chronic or progressive disease or condition

diabetic end-organ damage

predictions of end-organ function and failure in severe sepsis

—G. J. Slotman

end organ

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noun

: a structure forming the peripheral terminus of a path of nerve conduction and consisting of an effector or a receptor with its associated nerve terminations