endogenous

adjective

en·​dog·​e·​nous en-ˈdä-jə-nəs How to pronounce endogenous (audio)
1
: growing or produced by growth from deep tissue
endogenous plant roots
2
a
: caused by factors inside the organism or system
suffered from endogenous depression
endogenous business cycles
b
: produced or synthesized within the organism or system
an endogenous hormone
endogenously adverb

Did you know?

When biologists need to make a distinction between things that are produced within a cell or organ and things that affect it from the outside, they use the terms endogenous and exogenous. It used to be thought, for instance, that mutations in cells always resulted from exogenous causes, until it was discovered that substances in the body, including those called oxidants, could cause them endogenously as well. "Circadian rhythms"—the regular cycles, roughly 24 hours in length, that plants, animals, and humans rely on to regulate their days—are endogenously generated and don't actually depend on the sun for their timing.

Examples of endogenous in a Sentence

Recent Examples on the Web This dynamic begins in infancy: babies literally cannot modulate their stress system without nurturing touch from caregivers, which releases endogenous opioids and oxytocin, creating a sense of comfort and safety. Maia Szalavitz, Scientific American, 17 Sep. 2024 And during scary or stressful experiences, endogenous, or self-generated, opioids known as endorphins and enkephalins are released in the brain. Maia Szalavitz, Scientific American, 17 Sep. 2024 There are two primary types of Cushing syndrome: exogenous and endogenous, which are differentiated based on the cause of the disorder. Madeline Nguyen, The Arizona Republic, 12 June 2024 In addition to being the active ingredient in ayahuasca, DMT is an endogenous molecule synthesized naturally in mammalian brains. Jon Brodkin, Ars Technica, 2 Oct. 2023 See all Example Sentences for endogenous 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'endogenous.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1830, in the meaning defined at sense 1

Time Traveler
The first known use of endogenous was in 1830

Dictionary Entries Near endogenous

Cite this Entry

“Endogenous.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endogenous. Accessed 5 Nov. 2024.

Medical Definition

endogenous

adjective
en·​dog·​e·​nous en-ˈdäj-ə-nəs How to pronounce endogenous (audio)
variants also endogenic
1
: growing from or on the inside
endogenous spores
2
: caused by factors within the body or mind or arising from internal structural or functional causes
endogenous malnutrition
endogenous psychic depression
3
: relating to or produced by metabolic synthesis in the body
endogenous opioids
endogenous amino acids
compare exogenous
endogenously adverb

More from Merriam-Webster on endogenous

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