: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line

Examples of first-line in a Sentence

surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The American College of Obstetricians and Gynecologists considers biopsies a first-line test for postmenopausal bleeding in people at high risk for cancer.9 Taking a tissue sample helps your provider detect abnormalities, including cancerous cells. Jess Sims, Health, 26 Dec. 2024 Bristol-Myers Squibb said that the European Commission has approved Opdivo plus Yervoy — two drugs that can be used in combination for treating certain kinds of cancer — for the first-line treatment of adult patients with metastatic colorectal cancer. Zev Fima, CNBC, 23 Dec. 2024 The over-the-counter analgesic, sold as Tylenol or Panadol among other brand names, is the standard, first-line treatment for pain and fever. New Atlas, 15 Dec. 2024 These efforts, commonly referred to as market shaping, have driven the price of first-line HIV treatments down to as low as $37 per year, down from nearly $10,000 two decades ago. Peter Sands, Forbes, 29 Nov. 2024 See all Example Sentences for first-line 

Word History

First Known Use

1919, in the meaning defined above

Time Traveler
The first known use of first-line was in 1919

Dictionary Entries Near first-line

Cite this Entry

“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 3 Jan. 2025.

Medical Definition

first-line

adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
Last Updated: - Updated example sentences
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