: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line

Examples of first-line in a Sentence

surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Over-the-Counter and Home Remedy Options Topical treatments are first-line treatments for scalp psoriasis.14 Many are OTC and do not need a prescription. Lana Barhum, Verywell Health, 28 Feb. 2025 The analysis found spending on metformin, an older first-line oral drug for Type 2 diabetes that's available as a generic, decreased 5% over the five years studied, to $623 million. Adriel Bettelheim, Axios, 25 Feb. 2025 The 29-year-old is a dynamic top-six forward with first-line talent and a second-line history. Murat Ates, The Athletic, 20 Feb. 2025 Miller’s arrival with the Rangers and his installment as the first-line center between Artemi Panarin and Mika Zibanejad added to the buzz that always comes with a B’s-Rangers weekend game at the Garden. Steve Conroy, Boston Herald, 1 Feb. 2025 See All Example Sentences for first-line

Word History

First Known Use

1919, in the meaning defined above

Time Traveler
The first known use of first-line was in 1919

Browse Nearby Words

Cite this Entry

“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 10 Mar. 2025.

Medical Definition

first-line

adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
Last Updated: - Updated example sentences
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