1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Individuals with high-grade spondylolisthesis, or those who experience severe pain that impacts walking, standing or movement that has not improved with nonsurgical treatments, may receive a spinal fusion. Alyssa Goldberg, USA TODAY, 11 Dec. 2024 Spondylolisthesis can be considered a low-grade or high-grade condition depending on how much the bone slips out of place, and those with a high-grade slip are more likely to experience significant pain, nerve injury and even require surgery to relieve their symptoms. Ty Roush, Forbes, 10 Dec. 2024 The common thread is the intertwining of high-grade engineering and historical reference, in an iteration that doesn’t indulge in hyperrealistic fakery or honeyed nostalgia. Justin Davidson, Curbed, 4 Dec. 2024 On the soothing side of things, Hydra-Cool Serum soothes irritation with high-grade hyaluronic acid, centella asiatica, aloe vera, menthol, and cucumber extract, delivered with a cooling feeling when applied to the face, like a splash of cold water. Conçetta Ciarlo, Vogue, 3 Dec. 2024 See all Example Sentences for high-grade 

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Dictionary Entries Near high-grade

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 22 Dec. 2024.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

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