methylation

noun

meth·​yl·​a·​tion ˌme-thə-ˈlā-shən How to pronounce methylation (audio)
: the introduction of a methyl radical into a substance
The methylation of metals (that is, the substitution of a metal atom for the hydrogen atom of the hydroxyl group of a methyl alcohol molecule) can result in the metal's becoming volatile.Corale L. Brierley
especially : dna methylation
As cells begin to specialize into adult tissues, methylation seems to inactivate genes that are no longer needed. John Travis

Examples of methylation in a Sentence

Recent Examples on the Web
These examples are automatically compiled from online sources to illustrate current usage. Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Vegan Diet Reduces Biological Age Markers Overall, the twins who went vegan saw a significant reduction in markers of biological age based on changes in DNA methylation. Lisa Rapaport, EverydayHealth.com, 29 July 2024 Some changes that happen with DNA methylation may age the body faster, while others may slow aging down. Lisa Rapaport, EverydayHealth.com, 29 July 2024 In this case, the DNA methylation deactivates HNF4A, a gene that helps promote the proper function of many organs. Marta Musso, WIRED, 17 July 2024 This can be done through chemical processes methylation, which turns genes on, or demethylation, which turns genes off. Allison Deangelis, STAT, 4 Jan. 2024 See all Example Sentences for methylation 

Word History

First Known Use

1855, in the meaning defined above

Time Traveler
The first known use of methylation was in 1855

Dictionary Entries Near methylation

Cite this Entry

“Methylation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methylation. Accessed 16 Nov. 2024.

Medical Definition

methylation

noun
meth·​yl·​ation ˌmeth-ə-ˈlā-shən How to pronounce methylation (audio)
: introduction of the methyl group into a chemical compound
especially : dna methylation
methylate transitive verb
methylated; methylating
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