1
a
: a hybrid between a horse and a donkey
especially
: the offspring of a male donkey and a mare
b
: a self-sterile plant whether hybrid or not
c
: a usually sterile hybrid
2
: a very stubborn person
3
: a machine for simultaneously drawing and twisting fiber into yarn or thread and winding it into cops
4
slang
: a person who smuggles or delivers illicit substances (such as drugs)
variants
or less commonly Mule
plural mules also Mules
: moscow mule
The marvelous take on a classic mule swaps ginger beer for ginger kombucha … for a crisp, fresh-tasting award-worthy cocktail …—PR Newswire
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Merriam-Webster unabridged
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