open-label

adjective

open-la·​bel ˌō-pən-ˈlā-bəl How to pronounce open-label (audio)
: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject
an open-label multicenter study
compare double-blind, single-blind

Examples of open-label in a Sentence

Recent Examples on the Web
These examples are automatically compiled from online sources to illustrate current usage. Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Two more died during a subsequent open-label safety study, in which everyone could opt for donanemab. science.org, 3 July 2024 Of these, 12 participants completed the study and enrolled in the open-label extension study. Sacramento Bee, 3 Apr. 2024 While the idea of the placebo response goes back as far as the ancient Greeks, the open-label placebo has a more recent history. Tom Vanderbilt, WIRED, 19 Dec. 2023 The study — an open-label, non-randomized trial with a very small sample size — was published in the International Journal of Antimicrobial Agents on March 20. Abby Ohlheiser, Washington Post, 23 Mar. 2023

Word History

First Known Use

1979, in the meaning defined above

Time Traveler
The first known use of open-label was in 1979

Dictionary Entries Near open-label

Cite this Entry

“Open-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/open-label. Accessed 17 Nov. 2024.

Medical Definition

open-label

adjective
: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject
long-term open-label studies
compare double-blind, single-blind
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!