polysubstance
noun
poly·sub·stance
-ˈsəb-stən(t)s 
often attributive
: a group of substances used often indiscriminately by a substance abuser
has a polysubstance dependence problem
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“Polysubstance.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/polysubstance. Accessed 5 Nov. 2024.
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