protease inhibitor

noun

: a substance that inhibits the action of a protease
specifically : any of various drugs (such as indinavir) that inhibit the action of the protease of HIV so that the cleavage of viral proteins into mature functional infectious particles is prevented and that are used especially in combination with other agents in the treatment of HIV infection

Examples of protease inhibitor in a Sentence

Recent Examples on the Web
These examples are automatically compiled from online sources to illustrate current usage. Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Other ideas for treatments include using protease inhibitors to kill the virus, or stopping it from binding to the ACE2 receptors on human cells. Michele Cohen Marill, WIRED, 28 Apr. 2020 The challenges that remain By the late 1990s, the availability of protease inhibitors led AIDS death rates in the U.S. to plummet. Marc Ramirez, USA TODAY, 12 Oct. 2024 Later that year, the F.D.A. evaluated a new protease inhibitor that was still in early-stage trials. Gideon Lewis-Kraus, The New Yorker, 19 June 2023 The gene’s technical name, epididymal protease inhibitor, is usually shortened to the friendlier EPPIN. Gabe Allen, Discover Magazine, 9 Feb. 2022 See all Example Sentences for protease inhibitor 

Word History

First Known Use

1943, in the meaning defined above

Time Traveler
The first known use of protease inhibitor was in 1943

Dictionary Entries Near protease inhibitor

Cite this Entry

“Protease inhibitor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/protease%20inhibitor. Accessed 20 Nov. 2024.

Medical Definition

protease inhibitor

noun
: a substance that inhibits the action of a protease
specifically : any of various drugs (as indinavir or saquinavir) that inhibit the action of HIV protease so that cleavage of viral proteins into mature infectious particles is prevented and that are used especially in combination with other antiretroviral agents in the treatment of HIV infection

More from Merriam-Webster on protease inhibitor

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!