vaginectomy

noun

vag·​i·​nec·​to·​my ˌvaj-ə-ˈnek-tə-mē 

plural vaginectomies

: partial or complete surgical excision of the vagina

Researches say one of every 1,000 DES daughters will develop vaginal cancer by age 36. If detected early, it is treatable, though some cases result in hysterectomies or partial vaginectomies.

—Renee Graham, The Boston Globe

called also colpectomy