How to Use oligonucleotide in a Sentence

oligonucleotide

noun
  • To that end, the researchers turned to something called antisense oligonucleotides.
    Lydia Denworth, Scientific American, 3 Mar. 2020
  • The newest oligonucleotide drugs are designed to tackle rare diseases.
    Lydia Denworth, Scientific American, 3 Mar. 2020
  • The company's encoding starts with a library of dozens to hundreds of short pieces of DNA called oligos (short for oligonucleotide).
    John Timmer, Ars Technica, 15 Sep. 2022
  • But any chain that is short—usually 15 to 20 nucleotides—is considered an oligonucleotide.
    Lydia Denworth, Scientific American, 3 Mar. 2020
  • But one patient advocacy group has publicly shared that Yu’s team has designed an oligonucleotide for a toddler with ataxia-telangiectasia, a neurodegenerative disorder, and hoped to begin to treat her this fall.
    Jocelyn Kaiser, Science | AAAS, 9 Oct. 2019
  • An alternative treatment, drugs based on chemicals known as antisense oligonucleotides, is in clinical trials.
    Nicholas Wade, New York Times, 31 Dec. 2015
  • Upon receipt, the sequence is run through biosafety and biosecurity checks, and ultimately constructed through the enzymatic assembly of shorter oligonucleotide chains.
    Jeffrey Marlow, WIRED, 31 Mar. 2015
  • The drug is a synthetic genetic molecule — known as an oligonucleotide — similar to Biogen’s therapy for spinal muscular atrophy, Spinraza.
    Ryan Cross, BostonGlobe.com, 8 Dec. 2022
  • Krainer is co-founder of Stoke Therapeutics, a company focused on treating severe genetic disease using antisense oligonucleotides.
    Bret Stetka, Scientific American, 15 Aug. 2019

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'oligonucleotide.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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