1
as in sadness
a state or spell of low spirits
in despondency because he couldn't seem to settle into a lasting relationship
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2
as in despair
the state of being discouraged
in their despondency they seemingly forgot that losing teams can become winning teams in a single season
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3
as in desperation
utter loss of hope
never once gave into despondency and self-pity during her long recovery from her injuries in the car crash
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Merriam-Webster unabridged
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