1
as in exploding
to break open or into pieces usually because of internal pressure
specialists were able to deactivate the bomb before it went off
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2
as in progressing
to move forward along a course
the wedding went off without so much as a single glitch
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3
as in departing
to leave a place often for another
don't go off without telling us where we can find you
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Merriam-Webster unabridged
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