1
as in to guess
to decide the size, amount, number, or distance of (something) without actual measurement
if we suppose a minimum profit of $10,000 from the charity auction, we should be able to pay for the family's medical expenses
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2
as in to assume
to form an opinion from little or no evidence
what do you suppose he's going to do with the prize money he won?
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3
as in to think
to have as an opinion
voters wrongly supposed that the new mayor would be opposed to letting hazardous waste be transported through the city
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4
as in to say
to take as true or as a fact without actual proof
had always supposed that her father would bequeath the family farm to her
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Merriam-Webster unabridged
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