antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Graham was careful not to antagonize Johnson, who can't afford to lose more than one GOP vote on anything these days. Axios, 7 Feb. 2025 Venezuela’s opposition leaders, while careful not to antagonize the Trump administration, could not hide their disappointment. Andres Oppenheimer, Miami Herald, 31 Jan. 2025 Trump’s unconventional foreign policy views and willingness to antagonize allies are also likely to create challenges for intelligence sharing with foreign partners. Peter Schroeder, Foreign Affairs, 17 Jan. 2025 Indeed, there are cabbies like Joe Fong, 45, who sees no value in antagonizing his customers and has tried to adapt to his passengers’ needs. David Pierson, New York Times, 5 Jan. 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 1 Mar. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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