naloxone

noun

nal·​ox·​one na-ˈläk-ˌsōn 

: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C₁₉H₂₁NO₄·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web

The state is putting 3,000 fentanyl harm prevention kits, plus naloxone, in a vending machine on the University of Arkansas campus. —Alex Golden, Axios, 31 Oct. 2024

The kits include two doses of intranasal naloxone, a resource card with a QR code to the program’s webpage, how to sign up for text alerts about an overdose surge in Marion County and educational materials on recognizing an overdose and administering naloxone. —Sarah Nelson, The Indianapolis Star, 30 July 2024

Use of opioid settlement funds has been varied and not always transparent to date, ranging from investments in residential treatment, naloxone, and prevention programs in schools to law enforcement spending or filling old budget gaps. —Sarah E. Wakeman, STAT, 19 July 2024

According to a criminal complaint, the surviving children had to be given the overdose reversal drug naloxone, known by the brand name Narcan. —Antonio Planas, NBC News, 17 Oct. 2024

Word History

Etymology

N-allyl + hydroxy- + -one

First Known Use

1964, in the meaning defined above

Medical Definition

naloxone

noun

nal·​ox·​one nal-ˈäk-ˌsōn  ˈnal-ək-ˌsōn 

: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C₁₉H₂₁NO₄·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.