naltrexone

noun

nal·​trex·​one nal-ˈtrek-ˌsōn 

: a synthetic opiate antagonist C₂₀H₂₃NO₄ administered in the form of its hydrochloride

Examples of naltrexone in a Sentence

Recent Examples on the Web

While the research is ongoing, Leggio points to medications such as naltrexone, that the FDA has already approved to treat alcohol use disorder. —Allison Aubrey, NPR, 2 Dec. 2024

Bupropion/naltrexone: This combination drug, sold under the brand name Contrave, affects the brain's hunger and reward centers to reduce cravings and overall food intake. —Jay N. Yepuri, Verywell Health, 9 Sep. 2024

Interestingly, the effects of semaglutide on drinking were stronger than two older anti-addiction drugs that are also used for weight loss: naltrexone and topiramate. —Lisa Rapaport, EverydayHealth.com, 17 June 2024

This might also explain why the study found semaglutide better at reducing the risk of alcohol use disorder than naltrexone or topiramate, Simmons adds. —Lisa Rapaport, EverydayHealth.com, 17 June 2024

Word History

Etymology

N-allyl + trex- (as in methotrexate) + -one

First Known Use

1973, in the meaning defined above

Medical Definition

naltrexone

noun

nal·​trex·​one nal-ˈtrek-ˌsōn 

: a synthetic opiate antagonist administered especially in the form of its hydrochloride C₂₀H₂₃NO₄·HCl to maintain a drug-free state in detoxified opiate-dependent patients or to maintain abstinence in alcohol-dependent patients