1
as in disease
an abnormal state that disrupts a plant's or animal's normal bodily functioning
hoping that the doctor will be able to accurately diagnose my trouble
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Relevance
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2
as in threat
something that may cause injury or harm
that wild dog is trouble, so stay away
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3
as in problem
something that requires thought and skill for resolution
the police officers first broke up the fight and then asked what the trouble was
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4
as in effort
the active use of energy in producing a result
please, don't go to all that trouble just for me
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5
as in risk
the state of not being protected from injury, harm, or evil
if you think your brother might be in trouble, then let's go check up on him
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1
as in to worry
to experience concern or anxiety
don't trouble about me—I'll be fine
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2
as in to bother
to cause discomfort to or trouble for
I hate to trouble you, but would you mind moving for a minute so I can sweep under your chair?
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Merriam-Webster unabridged
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